Why Prilosec OTC

The #1 Doctor Recommended OTC Acid Reducer

Our trusted formula has provided relief for millions of frequent heartburn sufferers. We focus on results — blocking heartburn before it begins so you can live life to the fullest.*

Find out what sets us apart.

Proven Strength

How strong is Prilosec OTC? See the results of patient studies.

How Prilosec OTC Works

Watch a short demo illustrating how Prilosec OTC works to fight heartburn.

Our History

View Prilosec OTC history in the fight against frequent heartburn.

Read Our Package

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Easy-to-Open Package

See how to open our package in three easy steps.

Save with Medicare Part D

Learn how over-the-counter medicines like Prilosec OTC can help you save.

Free Prilosec OTC Sample

Start blocking heartburn before it begins.*

Buy Prilosec OTC Now

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* It’s possible with Prilosec OTC. Use as directed for 14 days for treating frequent heartburn.

  Wolters Kluwer (Acid reducer category).